When your ileocolic valve between
small and large intestines empties into a hernial
excursion of the latter, you get some very loud gurgling noises.
These feel like a cat on your lap (well, your right
lap) purring. For a second every 10-30 seconds.
As long as Mr. Appendix is ok, we're cool. Since it was last November 2011 (or 2010?), I'm good.
Entropy always wins. Everyone dies of something.
(5 of plumbing for every cancer, but I've shown that you will eventually (in the mathematical sense) eventually get cancer. At least as modern Western it probably won't be disease or violence, war, famine, or plague.